A case report of monitoring PSA level changes in two prostate cancer patients treated with Mountain Ginseng Pharmacopuncture and Sweet Bee Venom along with western anticancer therapy

  • cc icon
  • ABSTRACT

    Objectives:

    The purpose of this report is to find out how Mountain Ginseng Pharmacopuncture(MGP) and Sweet Bee Venom(SBV) treatments are effective on prostate cancer patients by monitoring Prostate specific antigen(PSA) values.

    Methods:

    We treated two prostate cancer patients with MGP and SBV from October 2008 to April 2011. One patient had localized prostate cancer, the other was in the terminal stage of prostate cancer with lung and bone metastasis and both had been receiving western anticancer therapy. We had monitored the changes of PSA value.

    Results:

    In case 1, MGP and SBV treatments seemed to be helpful in preventing the recurrence of localized prostate cancer. In case 2, PSA value was decreased by MGP treatment.

    Conclusions:

    It is conceivable that MGP and SBV are effective treatments for patients with prostate cancer.


  • KEYWORD

    Prostate cancer , Mountain Ginseng Pharmacopuncture , Sweet Bee Venom , Prostate specific antigen

  • 1. 2010 Annual Report of the Korea Central Cancer Registry (Cancer statistics, 2008). P.21-27 google
  • 2. Oh HJ, Song HS 2010 Bee venom inhibits PC-3 cell proliferation through induction of apoptosis via inactivation of NF - κB. [The Journal of Korean Acupuncture & Moxibustion Society] Vol.27 P.1-13 google
  • 3. Yang CY, Song HS 2010 Bee venom inhibits prostate cancer growth in LNCaP xenografts via apoptosis. [The Journal of Korean Acupuncture & Moxibustion Society] Vol.13 P.15-35 google doi
  • 4. Hur KY, Song HS 2011 Bee venom inhibits DU- 145 cell proliferation through induction of apoptosis. [The Journal of Korean Acupuncture & Moxibustion Society] Vol.28 P.111-119 google
  • 5. Ryu YJ, Lee KH, Kwon KR, Lee YH, Sun SH, Lee SJ 2010 Mountain ginseng pharmacopuncture treatment on three amyotrophic lateral sclerosis patients -case report-. [Journal of Pharmacopuncture] Vol.13 P.119-128 google doi
  • 6. 2008 Pharmacopuncturology. P.70-76 google
  • 7. 간계내과학 P.176-177 google
  • 8. 2011 Committee for new health technology, Committee for Iodine- 125 Permanent Implant for prostate cancer, Division of new Health Technology Assessment in National Evidence-based Healthcare Collaborating Agency. Iodine-125 permanent implant for prostate cancer. new Health Technology Assessment report. P.1-204 google
  • 9. Lee KO, Kim KI, Lee KP 1997 Development of enzyme immuno assay for analysis of free prostate specific antigen in serum. [Korean J. Biomed. Lab. Sci.] Vol.3 P.107-114 google
  • 10. Kwon DY, Seo CG, Kim BS, Kwak JH, Kim MS, Choi WI, Han SB, Song HS, Jeon YJ 2000 A case of endobronchial metastasis from prostatic carcinoma. Tuberculosis and Respiratory Diseases. [Tuberculosis and Respiratory Diseases] Vol.49 P.502-507 google
  • 11. Ha HK, Yun CJ, Lee SS, Shin DG, Lee W, Lee ZZ, Chung MK 2009 Survival rates and related factors in men with hormone-refractory prostate cancer. [Korean Journal of Urology] Vol.50 P.649-655 google doi
  • 12. Park CM, Lee CH 2005 Prognostic factors of biochemical failure after radical radiotherapy for localized prostate cancer. [J Kyung Hee Univ Med Cent] Vol.21 P.43-50 google
  • 13. Kim JH, Lee SI, Park KW, Kim YS, Lee HY, Kong JH, La SS 2008 A case of prostate cancer with generalized lymphadenopathy and osteolytic bone metastases. [The Korean Journal of Internal Medicine] Vol.74 P.S107-S111 google
  • 14.
  • 15.
  • 16. Han KS, Cho KS, Lee SH, Hong SJ 2007 Estramustine phosphate based chemotherapy for hormone refractory prostate cancer. [Korean Journal of Urology] Vol.48 P.684-690 google doi
  • 17.
  • 18. Nam DW, Lee JD, Choi DY 2007 Study trends on acupuncture treatment of cancer. [The Journal of Korean Acupuncture & Moxibustion Society] Vol.24 P.209-216 google
  • 19. Kwon KR, Park CW, Ra MS, Cho CK 2005 Clinical observation of multiple metastatic cancer patient with hepatocellular carcinoma treated with cultivated wild ginseng herbal acupuncture therapy. [The Journal of Korean Acupuncture & Moxibustion Society] Vol.22 P.211-217 google
  • 20. Bang SH, Kwon KR, Yoo HS 2008 Two cases of con-small cell lung cancer treated with intravenous cultivated wild ginseng pharmacopuncture. [Journal of Pharmacopuncture] Vol.11 P.13-19 google doi
  • 21. Min BI, Kim HH, Seo IB, Kwon KR 2007 Antitumor effects and protective effects against doxorubicin- induced testicular toxicity of cultivated wild ginseng extract in the B16/ F10 melanoma-bearing C57BL/ 6 mice. [Journal of Pharmacopuncture] Vol.10 P.85-100 google
  • [Table 1.] Changes of PSA Values in Case 1.
    Changes of PSA Values in Case 1.
  • [Fig. 1.] Prostate MRI of Case 1: A. Extensive prostate cancer with extracapsular extension and seminal vesicle invasion. B. No demonstrable recurrent cancer in the prostate and no evidence of lympadenopathy or bony metastasis.
    Prostate MRI of Case 1: A. Extensive prostate cancer with extracapsular extension and seminal vesicle invasion. B. No demonstrable recurrent cancer in the prostate and no evidence of lympadenopathy or bony metastasis.
  • [Table 2.] Changes of PSA Values in Case 2.
    Changes of PSA Values in Case 2.
  • [Fig. 2.] Bone Scan of Case 2: A. October 2009. There were Disseminated bone metastasis on both pelvic bone, skull, multiple ribs, scapulae, multiple spines. B. May 2010. Slightly improved disseminated bone metastasis, since October 2009. C. March 2011. Slightly aggravation of disseminated bone metastasis, since May 2010. D. May 2011. No interval change of disseminated bone metastasis, since March 2011.
    Bone Scan of Case 2: A. October 2009. There were Disseminated bone metastasis on both pelvic bone, skull, multiple ribs, scapulae, multiple spines. B. May 2010. Slightly improved disseminated bone metastasis, since October 2009. C. March 2011. Slightly aggravation of disseminated bone metastasis, since May 2010. D. May 2011. No interval change of disseminated bone metastasis, since March 2011.